Does Hyperbaric Oxygen Administration Before or After Irradiation Decrease Side Effects of Irradiation on Implant Sites?

Tumerdem-Ulug B., Kuran I., Ozden B. C. , Mete O., Kemikler G., Aktas S., ...Daha Fazla

ANNALS OF PLASTIC SURGERY, cilt.67, sa.1, ss.62-67, 2011 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 67 Konu: 1
  • Basım Tarihi: 2011
  • Doi Numarası: 10.1097/sap.0b013e3181e6cfa4
  • Sayfa Sayıları: ss.62-67


Background: One of the main limitations of implant-based breast reconstruction is the high rate of complications such as capsular contracture and poor aesthetic outcome, due to adjuvant radiotherapy. Hyperbaric oxygen treatment (HBOT) has been used to assist wound healing in the prevention and treatment of the side effects of irradiation. We aimed to investigate this effect of HBOT on the capsule reaction and skin, applied before and after irradiation, following the placement of an implant under the dorsal skin of the rat.