A complementary biocompatibility evaluation of plasma sprayed dentine (DHA) and enamel derived hydroxyapatite (EHA) using fibroblasts

Oktar F., Zdrentu L., Petrescu S., Valerio P., Ozyegin L., Peker I.

BIOCERAMICS 18, PTS 1 AND 2, ss.619-622, 2006 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Basım Tarihi: 2006
  • Doi Numarası: 10.4028/www.scientific.net/kem.309-311.619
  • Dergi Adı: BIOCERAMICS 18, PTS 1 AND 2
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Aerospace Database, Applied Science & Technology Source, Communication Abstracts, Compendex, INSPEC, Metadex, Civil Engineering Abstracts
  • Sayfa Sayıları: ss.619-622
  • Marmara Üniversitesi Adresli: Hayır

Özet

Hydroxyapatite (HA) material, collected from human tooth, was calcined and then separated very easily to enamel HA (EHA) and dentine HA (DHA). The ERA and DHA were plasma sprayed on pre-prepared titanium implants. HeLa (a lineage malignant fibroblast cell) and primary fibroblast cells cell lines were used in this study. The results using fibroblasts from primary culture are interesting since the cells did not die or became apoptotic. However, this does not mean that the present method reveals the complete biocompatibility of the tested HA material. This study aimed to investigate if fibroblasts with fluorescent tests could be used as a secondary evaluation method for biocompatibity fibroblasts cell culture studies prior to osteoblasts cell culture.