Treatment with estrogen receptor agonist ERβ improves torsion-induced oxidative testis injury in rats.

Tamer, SEVİL; YILDIRIM, ALPER; Arabaci, Sule; Ciftci, Selin; Akin, Sena; Sari, Elif; Koroglu, M.; ERCAN, FERİHA; YÜKSEL, MERAL; ÇEVİK, ÖZGE; YEGEN, BERRAK

doi:10.1016/j.lfs.2019.02.056

Treatment with estrogen receptor agonist ERβ improves torsion-induced oxidative testis injury in rats.

Tamer S., YILDIRIM A., Arabaci S., Ciftci S., Akin S., Sari E., ...Daha Fazla

Life sciences, cilt.222, ss.203-211, 2019 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 222
Basım Tarihi: 2019
Doi Numarası: 10.1016/j.lfs.2019.02.056
Dergi Adı: Life sciences
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.203-211
Anahtar Kelimeler: Testicular torsion, Estrogen, Infertility, Sperm, Apoptosis, Oxidative injury, ISCHEMIA-REPERFUSION, TESTICULAR TORSION, GENE-EXPRESSION, NITRIC-OXIDE, ALPHA, MECHANISMS, AROMATASE, PARAMETERS, APOPTOSIS, LIGANDS
Marmara Üniversitesi Adresli: Evet

Özet

Aims: The purpose of the present study was to investigate the potential antioxidant, anti-apoptotic and sperm function-preserving effects of estrogen, estrogen receptor (ER) a and ER beta agonists in a rat model of testis torsion-detorsion (T/D).