The methanolic extract of Thymus praecox subsp. skorpilii var. skorpilii restores glucose homeostasis, ameliorates insulin resistance and improves pancreatic β-cell function on streptozotocin/nicotinamide-induced type 2 diabetic rats.

ÇAM M. E., Hazar-Yavuz A. N., Yildiz S., ERTAŞ B., Adakul B. A., TAŞKIN T., ...Daha Fazla

Journal of ethnopharmacology, cilt.231, ss.29-38, 2019 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 231
  • Basım Tarihi: 2019
  • Doi Numarası: 10.1016/j.jep.2018.10.028
  • Dergi Adı: Journal of ethnopharmacology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.29-38
  • Anahtar Kelimeler: Diabetes, Metabolism, Inflammation, Thymus praecox, STZ/NA, Medicinal plants, GLUTs, SGLTs, AMPK, PROXIMAL TUBULAR CELLS, GLUT2 GENE-EXPRESSION, IN-VITRO, CARAMANICUS JALAS, ESSENTIAL OIL, SODIUM, HYPERGLYCEMIA, TRANSPORTERS, COTRANSPORTER, INTESTINE
  • Marmara Üniversitesi Adresli: Evet

Özet

Ethnopharmacological relevance: Thymus praecox subsp. skorpilii var. skorpilii (syn. Thymus praecox subsp. jankae (Celak.) Jalas) is consumed as a Turkish folk medicine for the treatment of spasm, sore throat and shortness of breath, also having strong antioxidant activity and the leaves of the plant have been utilized for the treatment of diabetes as the decoction in Turkey.