Akademik Veri Yönetim Sistemi
Biomaterials for Neural Tissue Engineering, Oguzhan Gunduz,Cem Bulent Ustundag and Mustafa Sengor, Editör, Elsevier Science, Oxford/Amsterdam , Amsterdam, ss.125-149, 2023
Damage to the nervous system due to
illness or injury can cause serious and lasting loss of function or even fatal
consequences. It is necessary to develop new treatment strategies to restore
the function of the damaged nervous system. The optimal environment for
nerve cell proliferation and differentiation is provided by neural tissue
engineering. It aims to improve a new approximation for the therapy
of nervous system diseases. Compared to 2D cell culture techniques, 3D cell
culture systems ensure a more biomimetic environment and encourage more differentiation
of cells. However, certain cell culture parameters have limitations in
spatio-temporal control. With the advent of microfluidic systems, it can
control the spatio-temporal dispersion of physical and chemical signals at the
cellular level. In this section, microfluidic systems are explored as a
tool to target both physical and chemical injury and recreate the post-injury
environment, to study nerve injury at the cellular grade.