Methylsulfonyl Zn phthalocyanine: A polyvalent and powerful hydrophobic photosensitizer with a wide spectrum of photodynamic applications

Isci Ü., Beyreis M., Tortik N., Topal S. Z., Glueck M., Ahsen V., ...Daha Fazla

PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY, cilt.13, ss.40-47, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 13
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1016/j.pdpdt.2015.10.010
  • Dergi Adı: PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.40-47
  • Anahtar Kelimeler: Photodynamic therapy, Photodynamic inactivation, Phthalocyanine, Singlet oxygen generation, In vitro, INACTIVATION, THERAPY, FORMULATIONS, CANCER
  • Marmara Üniversitesi Adresli: Hayır

Özet

Background: The biomedical photodynamic principle is based on the light-induced and photosensitizer-mediated killing of unwanted or harmful cells by overproduction of reactive oxygen species. Motivated by the success of photodynamic therapy (PDT) against several types of tumors, further applications of this approach are constantly identified which require the design and synthesis of novel photosensitizers with specifically tailored properties for a particular clinical application.