A new hope for obesity management: Boron inhibits adipogenesis in progenitor cells through the Wnt/beta-catenin pathway


Dogan A., Demirci S., Apdik H., Bayrak O. F. , Gulluoglu Ş. , Tuysuz E. C. , ...Daha Fazla

METABOLISM-CLINICAL AND EXPERIMENTAL, cilt.69, ss.130-142, 2017 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 69
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1016/j.metabol.2017.01.021
  • Dergi Adı: METABOLISM-CLINICAL AND EXPERIMENTAL
  • Sayfa Sayıları: ss.130-142

Özet

Obesity is a worldwide medical problem resulting in serious morbidity and mortality involving differentiation of pre-adipocytes into mature adipocytes (adipogenesis). Boron treatment has been reported to be associated with weight reduction in experimental animals; however, its effects on pre-adipocyte differentiation and anti-adipogenic molecular mechanisms are unknown.