Association of serum paraoxonase activity with insulin sensitivity and oxidative stress in hyperthyroid and TSH-suppressed nodular goitre patients

Yavuz D. , Yuksel M., Deyneli O., Ozen Y., Aydin H., Akalin S.

CLINICAL ENDOCRINOLOGY, cilt.61, sa.4, ss.515-521, 2004 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 61 Konu: 4
  • Basım Tarihi: 2004
  • Doi Numarası: 10.1111/j.1365-2265.2004.02123.x
  • Sayfa Sayıları: ss.515-521


OBJECTIVE Low serum paraoxonase (PON) activity is thought to be a risk factor for the development of atherosclerosis. The present study was designed to evaluate PON1 activity and its relationship with preatherosclerotic markers such as lipid peroxidation and insulin resistance in hyperthyroid patients before and after propylthiouracil (PTU) treatment and in subjects with iatrogenic subclinical hyperthyroidism.