Iterated bootstrap procedure in individual bioequivalence


Communications Series A1: Mathematics and Statistics, cilt.68, sa.1, ss.583-594, 2018 (ESCI İndekslerine Giren Dergi) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 68 Konu: 1
  • Basım Tarihi: 2018
  • Doi Numarası: 10.31801/cfsuasmas.438407
  • Dergi Adı: Communications Series A1: Mathematics and Statistics
  • Sayfa Sayıları: ss.583-594


In this paper, we propose an iterating principle in the bootstrap method to assess the individual bioequivalence under 2x4 randomized crossover design. The finite sample properties of the proposed algorithm are illustrated by an extensive simulation study and a real-world example. Our findings reveal that the proposed idea have better performance than the classical percentile bootstrap confidence limits.