Enhanced mRNA expression of plasminogen activator inhibitor-1 in livedoid vasculopathy lesions

Agirbasli M., Goktay F., Peker İ., Gunes P., Aker F. V., AKKİPRİK M.

CARDIOVASCULAR THERAPEUTICS, cilt.35, sa.3, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 35 Sayı: 3
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1111/1755-5922.12255
  • Dergi Adı: CARDIOVASCULAR THERAPEUTICS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: Fibrinolysis, Plasminogen activator inhibitor 1, Plasminogen inactivators, Thrombosis, Topical administration, Vascular diseases, VASCULITIS, DISEASE, PAI-1, POPULATION, MUTATION, LEIDEN
  • Marmara Üniversitesi Adresli: Evet

Özet

AimThrombosis and inflammation play an important role in pathophysiology of livedoid vasculopathy (LV). Plasminogen activator inhibitor-1 (PAI-1) is the main physiological inhibitor of fibrinolysis and is a pivotal modulator in a broad range of biological processes.