EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY, cilt.53, sa.3, ss.431-437, 2017 (SCI-Expanded)
Objective/Background: Neointimal hyperplasia (NIH) remains one of the leading causes of graft failure after vascular anastomoses. Cytotoxic drugs, such as rapamycin and tacrolimus, have been shown to inhibit the development of NIH. In this study, the aim was to test the impact of a sustained releasing tacrolimus-chitosan-eluting suture on the development of NIH in a rat model.