T cell responses to 60/65 kDa heat shock protein derived peptides in Turkish patients with Behcet's disease


Direskeneli H., Eksioglu-Demiralp E., Yavuz S., Ergun T., Shinnick T., Lehner T., ...Daha Fazla

JOURNAL OF RHEUMATOLOGY, cilt.27, ss.708-713, 2000 (SCI İndekslerine Giren Dergi) identifier

  • Cilt numarası: 27 Konu: 3
  • Basım Tarihi: 2000
  • Dergi Adı: JOURNAL OF RHEUMATOLOGY
  • Sayfa Sayıları: ss.708-713

Özet

Objective. Sequence homology and cross reactivity between microbial and human heal shuck proteins (HSP) led to the concept that HSP might be involved in the etiopathogenesis of Behcet's disease (BD). We investigated T cell responses to 8 synthetic peptides derived from the mycobacterial 65 kDa and homologous human 60 kDa HSP in patients with BD.