The goal of this study was to investigate low level harmonic content with unipolar voltage switching and bipolar voltage switching methods. Hence, we designed a single-phase full-bridge inverter application with Pulse Width Modulation (PWM) technique by using Peripheral Interface Controller (PIC) microcontroller. To obtain sinusoidal control signal and control of the inverter parameters, a PIC16F877 microcontroller was utilized in conjunction with an inverter to perform these two different techniques. The LCD control display and PIC Basic Pro programming language were used for the user interface and to program the microcontroller, respectively. Due to the application of PIC based control technique, total harmonic amount was decreased and a smaller size inverter was designed with very high realibility, safety, and low cost. In this study, an appropriate algorithm for the control software was obtained and approved for the supervision. Software was utilized to control the inverter, scalar control and ramp function as well as to obtain sine signal control of many parameters. The operation principle of the applied system and designed circuits is reported.