New in vitro effects of clopidogrel on platelets in hyperlipidemic and healthy subjects
TURKISH JOURNAL OF HEMATOLOGY, cilt.27, sa.2, ss.99-108, 2010 (SCI-Expanded, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 27 Sayı: 2
- Basım Tarihi: 2010
- Doi Numarası: 10.5152/tjh.2010.07
- Dergi Adı: TURKISH JOURNAL OF HEMATOLOGY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.99-108
- Anahtar Kelimeler: Platelets, hyperlipidemia, clopidogrel, apolipoprotein A1, apolipoprotein B, oxidative stress, nitrites, phosphatidylserine, P-selectin, glycoproteins IIb/IIIa, LOW-DENSITY-LIPOPROTEIN, GLYCOPROTEIN IIB/IIIA, P-SELECTIN, NORMOLIPEMIC VOLUNTEERS, SECONDARY PREVENTION, ACTIVATED PLATELETS, BINDING, INHIBITION, EXPRESSION, APOPTOSIS
- Marmara Üniversitesi Adresli: Evet
Özet
Objective: We aimed to detect novel in vitro effects of clopidogrel on platelets by assessment of the following parameters: malondialdehyde, glutathione, nitrite, aggregation response, and expressions of P-selectin, fibrinogen, apolipoprotein A1, apolipoprotein B, and phosphatidylserine.