Yuksekdanaci O., Altan E., Yildiz F. M., Ilhan E., Evran S., Yildirim R., ...Daha Fazla
CHEMISTRYSELECT, cilt.11, sa.22, 2026 (SCI-Expanded, Scopus)
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Yayın Türü:
Makale / Tam Makale
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Cilt numarası:
11
Sayı:
22
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Basım Tarihi:
2026
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Doi Numarası:
10.1002/slct.202505758
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Dergi Adı:
CHEMISTRYSELECT
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Derginin Tarandığı İndeksler:
Academic Search Ultimate (EBSCO), Scopus, Science Citation Index Expanded (SCI-EXPANDED), Chemical Abstracts Core
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Marmara Üniversitesi Adresli:
Evet
Özet
ABSTRACT
This study presents the development of novel wound dressing membranes composed of hyaluronic acid (HA), sodium alginate (SA), and polycaprolactone (PCL) to address the multifaceted challenges of wound healing. Leveraging the synergistic properties of these materials, the designed wound dressings aim to provide an optimal balance of bioactivity and mechanical strength. The membranes were fabricated using extrusion‐based 3D printing technology, ensuring precision and reproducibility in the structural design. SEM analysis showed that the average pore sizes ranged from 724.15 ± 34.47 µm (PCL/SA) to 916.25 ± 59.42 µm (0.35 HA), indicating that the incorporation of HA influenced morphology. All groups exhibited pore dimensions suitable for tissue engineering applications. Chemical composition assessment using Fourier‐transform infrared spectroscopy (FTIR), thermal property evaluation through differential scanning calorimetry (DSC), and mechanical properties using tensile testing were investigated to evaluate the structural stability of the dressings under physiological conditions. The results demonstrated that the HA‐SA‐PCL membranes exhibit excellent biocompatibility and robust mechanical performance for wound management applications. Additionally, the study highlights the potential of 3D printing technology in producing customizable wound dressings, providing both structural and biological support for effective wound care.