Analysis of Three-Dimensional Radiotherapy Treatment Plans in Palliative Spinal Bone Irradiation


Andic F., Adli M. , Dirier A., Ispir E. B. , Ozturk P. A.

UHOD-ULUSLARARASI HEMATOLOJI-ONKOLOJI DERGISI, cilt.19, ss.36-41, 2009 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 19 Konu: 1
  • Basım Tarihi: 2009
  • Dergi Adı: UHOD-ULUSLARARASI HEMATOLOJI-ONKOLOJI DERGISI
  • Sayfa Sayısı: ss.36-41

Özet

The study aimed to analyze dosimetric data of patients received palliative spinal bone irradiation using three-dimensional (31)) treatment planning with respect to International Commission on Radiation Units and Measurements (ICRU) Report 50 recommendations. 3D treatment plans of 53 patients treated for spinal bone metastasis were included in the study. Sixty treatment plans approved by three physicians were analyzed. The spinal cord, esophagus and intestines were contoured prospectively if located in the treatment fields. The mean of minimum, maximum and mean planning target volume (PTV) doses were 91.0 +/- 4.6%, 117.7 +/- 7.6% and 105.7 +/- 3.9%, respectively. When the mean of minimum, maximum and mean PTV doses were compared according to the attending physicians, there was no statistically significant difference. When the treatment plans were compared according to the fields used, mean of minimum PTV doses were significantly lower and mean of maximum PTV doses were significantly higher in the single-posterior field plans than in the two-opposed field plans (p<0.001). The mean doses to the spinal cord were lower in the two-opposed field plans than in the single-posterior field plans (p<0.001). The mean doses of esophagus and intestines were higher (p<0.001) in two-opposed field plans than in single-posterior field plans, however, less than the prescribed dose. Treatment plans of palliative spinal bone irradiation approved by three physicians did not accomplish the ICRU Report 50 recommendations, despite using 3D radiotherapy planning. However, two-opposed field plans resulted in a better dose distribution close to ICRU Report 50 recommendations with tolerable doses to the spinal cord, esophagus and intestines.