Surveillance of Haemophilus influenzae among respiratory tract samples of Turkish children.


Yagci A. , Ilki A. , Akbenlioglu C., Ulger N. , Inanli S., Soyletir G., ...More

International journal of antimicrobial agents, vol.22, no.5, pp.548-50, 2003 (Journal Indexed in SCI Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 22 Issue: 5
  • Publication Date: 2003
  • Doi Number: 10.1016/s0924-8579(03)00242-5
  • Title of Journal : International journal of antimicrobial agents
  • Page Numbers: pp.548-50

Abstract

We conducted three prospective studies of Haemophilus influenzae in different groups of children. Pharyngeal swab samples were taken (i) from 1382 healthy infants and children between 0 and 10 years of age (group 1), attending well child clinics (n = 438), day care centres (n = 440) and elementary schools (n = 504), and (ii) from 322 children aged 2-10 years (group 2), clinically diagnosed as having upper respiratory tract infection. Pharyngeal swab samples and sinus aspirates were obtained from 49 children between 2 and 9 years of age (group 3), clinically diagnosed as having sinusitis. H. influenzae was isolated in similar rates from 315 (22.7%) of children in group 1, 72 (22.3%) of children in group 2 and 12 (24.4%) of children in group 3. Serotype b comprised 7, 5.2 and 2% of all H. influenzae isolates for group 1, 2 and 3, respectively. Production of beta-lactamase was detected in 1.0% of H. influenzae type b isolates in group 1, 1.2 and 6.1% of all isolates in group 2 and 3, respectively. There were no beta-lactamase negative ampicillin-resistant strains. (C) 2003 Elsevier B.V. and the International Society of Chemotherapy. All rights reserved.