Design and fabrication of electrospun polycaprolactone/chitosan scaffolds for ligament regeneration


Saatcioglu E., Ulag S. , Şahin A. , Yılmaz B. , Ekren N. , İnan A. T. , ...More

EUROPEAN POLYMER JOURNAL, vol.148, 2021 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 148
  • Publication Date: 2021
  • Doi Number: 10.1016/j.eurpolymj.2021.110357
  • Title of Journal : EUROPEAN POLYMER JOURNAL
  • Keywords: Anterior cruciate ligament (ACL), Chitosan, PCL, Ligament, Scaffold

Abstract

Tendon and ligament impairments are among the most familiar injuries of the knee with acute or chronic pain conditions. The defects of anterior cruciate ligament (ACL) stay a known clinical problem. In the present study, the electrospinning method was used to fabricate 10wt.%PCL/(1, 3, 5)wt.%Chitosan (CS) appropriate and biocompatible scaffolds with a similar connective ligament geometry and structure. 10wt.%PCL/3wt.%CS demonstrated higher tensile strength value (0.58854 MPa) than other scaffolds in the tensile test.