Protective effects of spironolactone against hepatic ischemia/reperfusion injury in rats


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atalay s., Soylu b., AYKAÇ A., VELİOĞLU ÖĞÜNÇ A. , ÇETİNEL Ş. , ÖZKAN N. , ...More

TURKISH JOURNAL OF SURGERY, vol.35, no.4, pp.285-292, 2019 (Journal Indexed in ESCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 35 Issue: 4
  • Publication Date: 2019
  • Doi Number: 10.5578/turkjsurg.4340
  • Title of Journal : TURKISH JOURNAL OF SURGERY
  • Page Numbers: pp.285-292
  • Keywords: Hepatic ischemia reperfusion, spironolactone, malondialdehyde, glutathione, cytokines, ISCHEMIA-REPERFUSION INJURY, MELATONIN PROTECTS, LIVER-INJURY, RECEPTORS, APOPTOSIS

Abstract

Objective: In the present study, it was aimed to study the antioxidant effects of spironolactone (SPL) to determine its possible protective effects in hepatic ischemia reperfusion injury.