Obestatin alleviates subarachnoid haemorrhage-induced oxidative injury in rats via its anti-apoptotic and antioxidant effects

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ERŞAHİN M., ÖZSAVCI D., ŞENER A., BİNGÖL ÖZAKPINAR Ö., Toklu H. Z., AKAKIN D., ...More

BRAIN INJURY, vol.27, no.10, pp.1181-1189, 2013 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 27 Issue: 10
• Publication Date: 2013
• Doi Number: 10.3109/02699052.2013.804199
• Journal Name: BRAIN INJURY
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus
• Page Numbers: pp.1181-1189
• Keywords: Apoptosis, obestatin, oxidative, stress, subarachnoid haemorrhage, BLOOD-BRAIN-BARRIER, COGNITIVE DYSFUNCTION, MESSENGER-RNA, GHRELIN, EXPRESSION, VASOSPASM, DAMAGE, STRESS, OXYHEMOGLOBIN, PROTECTS
• Marmara University Affiliated: Yes

Abstract

Objective: The aim was to investigate the putative anti-inflammatory and anti-apoptotic effect of obestatin in a rat model of subarachnoidal haemorrhage (SAH).