Synthesis and Anticancer Activity of New Hydrazide-hydrazoncs and Their Pd(II) Complexes

Kocyigit-Kaymakcioglu B., Yazici S. S., TOK F., Dikmen M., Engur S., Oruc-Emre E. E., ...Daha Fazla

LETTERS IN DRUG DESIGN & DISCOVERY, cilt.16, sa.5, ss.522-532, 2019 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 16 Sayı: 5
  • Basım Tarihi: 2019
  • Doi Numarası: 10.2174/1570180815666180816124102
  • Dergi Adı: LETTERS IN DRUG DESIGN & DISCOVERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.522-532
  • Anahtar Kelimeler: Hydrazone, metal-complexes, anticancer activity, MTT assay, real-time monitoring, proliferative system, IN-VITRO, PROTEIN-BINDING, PLATINUM(II) COMPLEXES, CRYSTAL-STRUCTURE, DNA-BINDING, PALLADIUM(II), DERIVATIVES, LIGANDS, PROLIFERATION, ANTIOXIDANT
  • Marmara Üniversitesi Adresli: Evet

Özet

Background: Hydrazones, one of the important classes of organic molecules, are pharmaceutical agents comprising -CO-NH-N=CH- group in the structure therefore and exhibiting significant biological activity.