Protective effect of chlorogenic acid on renal ischemia/reperfusion injury in rats.

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Atıf İçin Kopyala

Toprak T., Sekerci Ç. A., Aydın H., Ramazanoglu M., Arslan F., Basok B., ...Daha Fazla

Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica, cilt.92, sa.2, 2020 (ESCI)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 92 Sayı: 2
• Basım Tarihi: 2020
• Doi Numarası: 10.4081/aiua.2020.2.153
• Dergi Adı: Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica
• Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, EMBASE, MEDLINE, Directory of Open Access Journals
• Anahtar Kelimeler: Renal ischemia, Oxidative stress, Chlorogenic acid, Rat, ISCHEMIA-REPERFUSION INJURY, IN-VITRO, ANTIOXIDANT, EXTRACTS, DAMAGE
• Marmara Üniversitesi Adresli: Evet

Özet

Objectives: Ischemia/repetfusion (I/R) injury is a common cause of renal injury and to date, many pharmacological agents have been identified to decrease I/R injury. One of the potential compound that can target I/R injury is chlorogenic acid (CGA). It has potent anti-inflammatory, antibacterial, anti-oxidant, analgesic and antipyretic activities in in vitro experiments and in vivo (mama; models. The aim of the study was to investigate the protective characteristic of CGA on renal I/R injury.