Antioxidant Agent Quercetin Prevents Impairment of Bladder Tissue Contractility and Apoptosis in a Rat Model of Ischemia/Reperfusion Injury

TİNAY İ., Sener T. E., ÇEVİK Ö., Cadirci S., Toklu H., ÇETİNEL Ş., ...Daha Fazla

LUTS-LOWER URINARY TRACT SYMPTOMS, cilt.9, sa.2, ss.117-123, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 9 Sayı: 2
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1111/luts.12125
  • Dergi Adı: LUTS-LOWER URINARY TRACT SYMPTOMS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.117-123
  • Anahtar Kelimeler: ischemia reperfusion injury, quercetin, urinary bladder, ISCHEMIA-REPERFUSION INJURY, SUPEROXIDE-DISMUTASE ACTIVITY, SPINAL-CORD-INJURY, URINARY-BLADDER, FUNCTIONAL CONSEQUENCES, BIOCHEMICAL-CHANGES, OXIDANT DAMAGE, NITRIC-OXIDE, ISCHAEMIA/REPERFUSION, DYSFUNCTION
  • Marmara Üniversitesi Adresli: Evet

Özet

ObjectivesTo examine the possible protective effect of quercetin (QT), which is well known for its antioxidant and protective effects in circumstances of oxidative stress, on urinary bladder tissue in a rat model of ischemia/reperfusion (I/R) injury, which is a known factor for the development of lower urinary tract dysfunction partly mediated by the generation of free radicals causing oxidative damage.