Protective role of resveratrol against cisplatin induced ototoxicity in guinea pigs

YUMUŞAKHUYLU, ALİ; Yazici, Mine; Sari, Murat; Binnetoglu, Adem; Kosemihal, Ebru; Akdas, Ferda; ŞİRVANCI, SERAP; YÜKSEL, MERAL; Uneri, Cuneyd; Tutkun, Alper

doi:10.1016/j.ijporl.2011.12.021

Protective role of resveratrol against cisplatin induced ototoxicity in guinea pigs

YUMUŞAKHUYLU A. C., Yazici M., Sari M., Binnetoglu A., Kosemihal E., Akdas F., ...Daha Fazla

INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY, cilt.76, sa.3, ss.404-408, 2012 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 76 Sayı: 3
Basım Tarihi: 2012
Doi Numarası: 10.1016/j.ijporl.2011.12.021
Dergi Adı: INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.404-408
Anahtar Kelimeler: Resveratrol, Cisplatin, Ototoxicity, Auditory brainstem response, Reactive oxygen species, Scanning electron microscopy, ROUND WINDOW APPLICATION, D-METHIONINE, HAIR-CELLS, VITAMIN-E, ANTIOXIDANT, NEPHROTOXICITY, EXPRESSION, GROWTH, RATS
Marmara Üniversitesi Adresli: Evet

Özet

Objective: The aim of this study was to evaluate the effectiveness of systemic administration of resveratrol against cisplatin-induced ototoxicity in guinea pigs.