Protective role of resveratrol against cisplatin induced ototoxicity in guinea pigs


YUMUŞAKHUYLU A. C. , Yazici M., Sari M., Binnetoglu A., Kosemihal E., Akdas F., ...More

INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY, vol.76, no.3, pp.404-408, 2012 (Journal Indexed in SCI) identifier

  • Publication Type: Article / Article
  • Volume: 76 Issue: 3
  • Publication Date: 2012
  • Doi Number: 10.1016/j.ijporl.2011.12.021
  • Title of Journal : INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY
  • Page Numbers: pp.404-408
  • Keywords: Resveratrol, Cisplatin, Ototoxicity, Auditory brainstem response, Reactive oxygen species, Scanning electron microscopy, ROUND WINDOW APPLICATION, D-METHIONINE, HAIR-CELLS, VITAMIN-E, ANTIOXIDANT, NEPHROTOXICITY, EXPRESSION, GROWTH, RATS

Abstract

Objective: The aim of this study was to evaluate the effectiveness of systemic administration of resveratrol against cisplatin-induced ototoxicity in guinea pigs.