A Low-cost Biomarker-based SAW-Biosensor Design for Early Detection of Prostate Cancer

Şişman A., Gür E., Ozturk S., Enez B., Okur B., Toker O.

26th Anniversary World Congress on Biosensors (Biosensors), Gothenburg, İsveç, 25 - 27 Mayıs 2016, cilt.27, ss.248-249 identifier

  • Yayın Türü: Bildiri / Tam Metin Bildiri
  • Cilt numarası: 27
  • Doi Numarası: 10.1016/j.protcy.2017.04.106
  • Basıldığı Şehir: Gothenburg
  • Basıldığı Ülke: İsveç
  • Sayfa Sayıları: ss.248-249
  • Anahtar Kelimeler: Biosensor, Surface acoustic wave, acurate phase detection, MEMS
  • Marmara Üniversitesi Adresli: Evet

Özet

Early detection of prostate cancer is crucial for the treatment. Currently rectal examination, ultrasound and ELISA test for blood-PSA biomarker level are used for diagnosis. However these methods require professional assistance that makes point-of care (POC) testing impossible. A POC, low-cost, high-precision biosensor can increase the early-detection and survival rates. Recently, we have proposed a low-cost and an easy-to-use surface acoustic wave biosensor that enables the quantification of PSA level. In this study, we focused to the electronic circuitry and signal processing algorithms for accurate protein level assessment using cost efficient and low-profile hardware. Simplifying the hardware will potentially lead to the development of single chip monolithic integrated biosensor.