Pediatric Practice and Research, cilt.13, sa.2, ss.33-39, 2025 (Hakemli Dergi)
Aim: In peripheral intravenous catheterization applications, procedural problems may cause local or systemic infections. The aim of this study was to determine the antimicrobial effect of 5% Sodium Bicarbonate in skin antisepsis before catheterization.
Material and Method: The study was randomized, single blind and experimental. In the study, skin antisepsis was used with 5% sodium bicarbonate before peripheral intravenous catheterization. Chlorhexidine gluconate 2% and alcohol 70% were used as a comparison group. The catheter was inserted after antisepsis was applied. One and 24 hours after catheterization, skin swabs were taken and analyzed. Local and systemic infection f indings and vital signs were measured every 12 hours.
Results: 5% Sodium Bicarbonate showed antimicrobial effect in skin antisepsis. There was no evidence of systemic infection and vital signs were within normal limits. The most common bacterial subtype was Staphylococcus hominis, which was found in skin swabs of 8.1% of the children.
Conclusions: The 5% sodium bicarbonate may be an effective and cost-effective agent for skin antisepsis in children. It can be used for skin antisepsis before peripheral intravenous catheterization. The efficacy of different concentrations of sodium bicarbonate solutions should be investigated.