Interferon-gamma knockout fails to confer protection against obliteration in heterotopic murine tracheal allografts


Batirel H., Batirel S., Mitchell R., Swanson S.

JOURNAL OF HEART AND LUNG TRANSPLANTATION, cilt.24, sa.6, ss.658-664, 2005 (SCI-Expanded) identifier identifier identifier

Özet

Background: Interferon-gamma, produced by T-helper cells, activates macrophages and increases expression of major histocompatibility complex (MHC) products in acute and chronic rejection. We investigated the role of interferon-gamma in murine heterotopic tracheal allografts.