Interferon-gamma knockout fails to confer protection against obliteration in heterotopic murine tracheal allografts


Batirel H., Batirel S. , Mitchell R., Swanson S.

JOURNAL OF HEART AND LUNG TRANSPLANTATION, vol.24, no.6, pp.658-664, 2005 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 24 Issue: 6
  • Publication Date: 2005
  • Doi Number: 10.1016/j.healun.2004.04.013
  • Title of Journal : JOURNAL OF HEART AND LUNG TRANSPLANTATION
  • Page Numbers: pp.658-664

Abstract

Background: Interferon-gamma, produced by T-helper cells, activates macrophages and increases expression of major histocompatibility complex (MHC) products in acute and chronic rejection. We investigated the role of interferon-gamma in murine heterotopic tracheal allografts.