Minimally invasive thyroid anaplastic carcinoma with long survival.

UĞURLU M. Ü. , ERBARUT SEVEN İ. , Eren F., Yegen C. , Gulluoglu B. M.

Turkish journal of surgery, vol.34, no.4, pp.319-322, 2018 (Refereed Journals of Other Institutions) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 34 Issue: 4
  • Publication Date: 2018
  • Doi Number: 10.5152/turkjsurg.2017.3383
  • Title of Journal : Turkish journal of surgery
  • Page Numbers: pp.319-322


Anaplastic thyroid carcinoma is a highly lethal malignancy. Previously, only five cases of a noninvasive form of anaplastic thyroid carcinoma with excellent prognosis were reported, We report a case of a 68-year-old man who presented with a 3,8 cm thyroid nodule diagnosed by fine needle aspiration biopsy as poorly differentiated spindled and epithelial malignant cells, Lobectomy and isthmusectomy were performed, and the final diagnosis was micro-invasive anaplastic thyroid carcinoma arising in a poorly differentiated carcinoma, The patient remains disease-free after six years, even after hemithyroidectomy and radiation treatment. Noninvasive/micromvasive anaplastic thyroid carcinoma appears to be a different disease entity from classical anaplastic thyroid carcinoma, with favorable prognosis and long disease-free survival.