Alteration in humoral immunity is common among family members of patients with common variable immunodeficiency.

Karakoc-Aydiner E., ÖZEN A. O., Bans S., ercan h., ozdemir c., barlan i. b.

Journal of investigational allergology & clinical immunology, cilt.24, sa.5, ss.346-51, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 24 Sayı: 5
  • Basım Tarihi: 2014
  • Dergi Adı: Journal of investigational allergology & clinical immunology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.346-51
  • Anahtar Kelimeler: Allergy, Common variable immunodeficiency (CVID), Consanguinity, Family screening, Immunoglobulin A (IgA) deficiency, Hypogammaglobulinemia, SELECTIVE IGA DEFICIENCY, SUSCEPTIBILITY LOCUS, GENETIC-LINKAGE, CHILDREN, ASTHMA, ATOPY, ASSOCIATION, HAPLOTYPES, MUTATIONS, INFANTS
  • Marmara Üniversitesi Adresli: Evet

Özet

Background:The prevalence of primary immunodeficiency (PID) in the relatives of patients with common variable immunodeficiency (CVID) and IgA deficiency is high. Allergic disorders have been recorded in patients with humoral immunodeficiency. We aimed to determine the frequency of humoral immunodeficiency and atopy in the relatives of patients with CVID.