Coronavirus disease 2019 in patients with inborn errors of immunity: An international study

Meyts I., Bucciol G., Quinti I., Neven B., Fischer A., Seoane E., ...More

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, vol.147, no.2, pp.520-531, 2021 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 147 Issue: 2
  • Publication Date: 2021
  • Doi Number: 10.1016/j.jaci.2020.09.010
  • Journal Name: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, PASCAL, BIOSIS, CAB Abstracts, EMBASE, Food Science & Technology Abstracts, International Pharmaceutical Abstracts, MEDLINE, Veterinary Science Database
  • Page Numbers: pp.520-531
  • Keywords: SARS-CoV-2, COVID-19, primary immunodeficiencies, inborn errors of immunity, hypogammaglobulinemia, immune dysregulation
  • Marmara University Affiliated: Yes

Abstract

Background: There is uncertainty about the impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in individuals with rare inborn errors of immunity (IEI), a population at risk of developing severe coronavirus disease 2019. This is relevant not only for these patients but also for the general population, because studies of IEIs can unveil key requirements for host defense.