Comparison of telomere length and insulin-like growth factor-binding protein 7 promoter methylation between breast cancer tissues and adjacent normal tissues in Turkish women.

Kaya Z., AKKİPRİK M. , Karabulut S., Peker I., GÜLLÜ AMURAN G. , Ozmen T., ...More

Journal of clinical laboratory analysis, vol.31, no.5, 2017 (Journal Indexed in SCI Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 31 Issue: 5
  • Publication Date: 2017
  • Doi Number: 10.1002/jcla.22083
  • Title of Journal : Journal of clinical laboratory analysis


BackgroundBoth insulin-like growth factor-binding protein 7 (IGFBP7) and telomere length (TL) are associated with proliferation and senescence of human breast cancer. This study assessed the clinical significance of both TL and IGFBP7 methylation status in breast cancer tissues compared with adjacent normal tissues. We also investigated whether IGFBP7 methylation status could be affecting TL.