Serum high-sensitivity C-reactive protein, tumor necrosis factor-α, interleukin (IL)-1β, IL-17A and IL-23 levels in patients with hidradenitis suppurativa.


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Ozturk G. S. , Ergun T., Eyuboglu I. P. , Akkiprik M.

Cytokine, vol.144, pp.155585, 2021 (Journal Indexed in SCI Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 144
  • Publication Date: 2021
  • Doi Number: 10.1016/j.cyto.2021.155585
  • Title of Journal : Cytokine
  • Page Numbers: pp.155585
  • Keywords: Hidradenitis suppurativa, hs-CRP, TNF-alpha, IL-1 beta, IL-17A, IL-23

Abstract

Background: Hidradenitis suppurativa (HS) is a chronic, recurrent inflammatory skin disease that leads to scar formation. The immune pathogenesis of HS is not fully understood and inhibitors of tumor necrosis factor (TNF)-alpha, interleukin (IL)-17, IL-1, IL-23 can be used for treating HS. Identification of serum biomarkers may help understanding individual differences in HS pathogenesis, evaluating disease severity and developing more effective treatment methods.