Paraoxonase-1 and Coronary Heart Diseases

Tarcin Ö.

MARMARA MEDICAL JOURNAL, cilt.24, sa.1, ss.59-63, 2011 (ESCI) identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 24 Sayı: 1
  • Basım Tarihi: 2011
  • Doi Numarası: 10.5472/mmj.2010.01705.2
  • Dergi Adı: MARMARA MEDICAL JOURNAL
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.59-63
  • Anahtar Kelimeler: Paraoxonase-1, Coronary heart diseases, PON 1 polymorphism
  • Marmara Üniversitesi Adresli: Hayır

Özet

Serum Paraoxonase-1(PON1) level, an anti-oxidant enzyme, decreases with diseases related to coronary heart diseases (CAH) such as diabetes, hypertension, hyperlipidemia and smoking. All clinical studies which were performed in patients with CAH have shown significant low levels and activity of PON1. These studies suggest that the PON1 level might be a marker for CAH, but more prospective and case-controlled studies are needed on this subject.