The effect of phosphodiesterase-5 inhibition by sildenafil citrate on inflammation and apoptosis in rat experimental colitis

Karakoyun B., Uslu Ü., Ercan F. , Aydın M. Z. , Yüksel M. , Velioğlu Öğünç A. , ...More

LIFE SCIENCES, vol.89, pp.402-407, 2011 (Journal Indexed in SCI) identifier

  • Publication Type: Article / Article
  • Volume: 89
  • Publication Date: 2011
  • Doi Number: 10.1016/j.lfs.2011.07.005
  • Title of Journal : LIFE SCIENCES
  • Page Numbers: pp.402-407


Aims: To investigate the effect of sildenafil citrate (SIL) on the extent of tissue integrity, oxidant-antioxidant status and apoptosis in rats with colitis.