The effect of phosphodiesterase-5 inhibition by sildenafil citrate on inflammation and apoptosis in rat experimental colitis

Karakoyun, Berna; Uslu, Ünal; Ercan, FERİHA; Aydın, MEHMET; Yüksel, MERAL; Velioğlu Öğünç, AYLİZ; Alican, YAŞAR

doi:10.1016/j.lfs.2011.07.005

The effect of phosphodiesterase-5 inhibition by sildenafil citrate on inflammation and apoptosis in rat experimental colitis

Karakoyun B., Uslu Ü., Ercan F. , Aydın M. Z. , Yüksel M. , Velioğlu Öğünç A. , ...More

LIFE SCIENCES, vol.89, pp.402-407, 2011 (Journal Indexed in SCI)

Publication Type: Article / Article
Volume: 89
Publication Date: 2011
Doi Number: 10.1016/j.lfs.2011.07.005
Title of Journal : LIFE SCIENCES
Page Numbers: pp.402-407

Abstract

Aims: To investigate the effect of sildenafil citrate (SIL) on the extent of tissue integrity, oxidant-antioxidant status and apoptosis in rats with colitis.