Chitosan/Gold Hybrid Nanoparticles Enriched Electrospun PVA Nanofibrous Mats for the Topical Delivery of Punica granatum L. Extract: Synthesis, Characterization, Biocompatibility and Antibacterial Properties


Mohamady Hussein M. A. , Ulag S. , Abo Dena A. S. , Sahin A. , Grinholc M., Gunduz O. , ...More

INTERNATIONAL JOURNAL OF NANOMEDICINE, vol.16, pp.5133-5151, 2021 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 16
  • Publication Date: 2021
  • Doi Number: 10.2147/ijn.s306526
  • Title of Journal : INTERNATIONAL JOURNAL OF NANOMEDICINE
  • Page Numbers: pp.5133-5151
  • Keywords: gold nanoparticles, chitosan, Punica granatum, nanofiber, antibacterial, POLYVINYL-ALCOHOL, POLY(METHYL METHACRYLATE), GOLD NANOPARTICLES, WOUND DRESSINGS, POMEGRANATE, COMPOSITE, DIFFERENTIATION, COMPATIBILITY, PERFORMANCE, VISCOSITY

Abstract

Purpose: Intending to obtain Punica granatum L. extract (PE)-loaded drug delivery system of better impact and biomedical applicability, the current study reports the use of crosslinked PVA nanofibers (NFs) as platforms incorporating different amounts of biosynthesized PE-CS-gold nanoparticles (PE-CS-Au NPs).