Effects of selective COX-2 inhibitors on the gastric permeability of sucrose: a controlled study with placebo and ibuprofen

Ekenel, M; Avsar, E; Imeryuz, N; Yuksel, M; Haklar, GONCAGÜL; Kocakaya, O; Tozun, N

doi:10.1097/01.meg.0000050004.68425.6b

Effects of selective COX-2 inhibitors on the gastric permeability of sucrose: a controlled study with placebo and ibuprofen

Atıf İçin Kopyala

Ekenel M., Avsar E., Imeryuz N., Yuksel M., Haklar G., Kocakaya O., ...Daha Fazla

EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, cilt.15, sa.4, ss.403-406, 2003 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 15 Sayı: 4
Basım Tarihi: 2003
Doi Numarası: 10.1097/01.meg.0000050004.68425.6b
Dergi Adı: EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.403-406
Marmara Üniversitesi Adresli: Evet

Özet

Objective Acute and chronic use of non-steroidal anti-inflammatory drugs can increase gastrointestinal permeability. Celecoxib, which selectively inhibits the enzyme cyclooxygenase-2, is a novel anti-inflammatory drug with minimal gastrointestinal toxic effects while retaining anti-inflammatory efficacy. Our aim was to assess the potential effects of celecoxib on gastric permeability in comparison with placebo and ibuprofen.