TURKISH JOURNAL OF BIOCHEMISTRY, vol.45, pp.515-523, 2020 (Journal Indexed in SCI)
Article / Article
Title of Journal :
TURKISH JOURNAL OF BIOCHEMISTRY
Breast cancer, PI3K, PIK3CA, HRM, Candidate genes, CELL-PROLIFERATION, ASSOCIATION
Objective: A high frequency of PI3K signalling pathway abnormalities and TP53 mutations are critical in the development and progression of breast cancer (BCa). We aimed to detect PIK3CA and TP53 mutations via an expression analysis of PIK3R1, PTEN and SALL4 and correlate the expression of these genes with clinical parameters of BCa.