Iron preloading aggravates nutritional steatohepatitis in rats by increasing apoptotic cell death

Imeryuz N., Tahan V., Sonsuz A., Eren F. , Uraz S., Yuksel M. , ...More

JOURNAL OF HEPATOLOGY, vol.47, no.6, pp.851-859, 2007 (Journal Indexed in SCI) identifier

  • Publication Type: Article / Article
  • Volume: 47 Issue: 6
  • Publication Date: 2007
  • Doi Number: 10.1016/j.jhep.2007.06.018
  • Title of Journal : JOURNAL OF HEPATOLOGY
  • Page Numbers: pp.851-859


Background/Aims: High serum ferritin and liver iron concentrations were found in some patients with NASH, suggesting a role for iron as a co-factor that aggravates liver injury. The aim of this study is to investigate the effects of parenteral iron in a rat model of NASH induced by a methionine choline deficient diet (MCDD).