Aprepitant in the Treatment of Subacute Sclerosing Panencephalitis: A Randomized, Double-Blind, Placebo-Controlled Study

Oncel I., SANCAR M. , Konuskan B., Arioz F., TEZCAN S. , Arman-Kandirmaz E. , ...More

Pediatric Neurology, vol.110, pp.59-63, 2020 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 110
  • Publication Date: 2020
  • Doi Number: 10.1016/j.pediatrneurol.2020.05.009
  • Title of Journal : Pediatric Neurology
  • Page Numbers: pp.59-63
  • Keywords: Subacute sclerosing panencephalitis, Neurokinin-1 receptor, Aprepitant, Measles virus, SSPE, CEREBROSPINAL-FLUID, SSPE


Background: Aprepitant is a neurokinin-1 receptor antagonist approved for the treatment of chemotherapy-induced nausea. We aimed to investigate the safety and efficacy of aprepitant in patients with subacute sclerosing panencephalitis.