Evaluation of the wound healing potential of Aloe vera-based extract of Nerium oleander


Akgün Ölmez S. G., Aydemir S., Özkan N., Yüksel M., Sardas S.

NORTHERN CLINICS OF ISTANBUL, cilt.4, ss.205-212, 2017 (Hakemli Dergi) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 4
  • Basım Tarihi: 2017
  • Doi Numarası: 10.14744/nci.2017.94914
  • Dergi Adı: NORTHERN CLINICS OF ISTANBUL
  • Sayfa Sayıları: ss.205-212
  • Anahtar Kelimeler: Anti-inflammatory effect, antioxidant effect, DNA damage, nerium oleander, DOUBLE-STRAND BREAKS, OXIDATIVE STRESS, BURN-INJURY, LIPID-PEROXIDATION, THERMAL-INJURY, SKIN INJURY, DNA-DAMAGE, CHO-CELLS, RATS, ANTIOXIDANT
  • Marmara Üniversitesi Adresli: Evet

Özet

OBJECTIVE: Nerium oleander (Apocynaceae) and Aloe vera (Liliaceae) are among the widely used herbal remedies for treating skin diseases and possess numerous activities such as antibacterial, antiviral, antifungal, and antioxidant. The aim of this study was to investigate the possible wound healing effect of Aloev era-based extract of the N. oleander leaf (NAE-8 (R)) based on its antioxidant, anti-inflammatory, and DNA repair capacity along with histological changes and to compare them with the traditional silver sulfadiazine treatment (SSD).