Ghrelin Alleviates Spinal Cord Injury in Rats Via Its Anti-inflammatory Effects

Ersahin M., Toklu H. Z. , ERZİK C. , AKAKIN D. , TETİK Ş. , ŞENER G. , ...More

TURKISH NEUROSURGERY, vol.21, no.4, pp.599-605, 2011 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 21 Issue: 4
  • Publication Date: 2011
  • Doi Number: 10.5137/1019-5149.jtn.4736-11.0
  • Title of Journal : TURKISH NEUROSURGERY
  • Page Numbers: pp.599-605


AIM: Spinal cord injury (SCI) leads to an inflammatory response that generates substantial secondary damage within the tissue besides the primary damage. Ghrelin, 28 amino-acid peptide, has been shown to modulate the release of proinflammatory cytokines and exert anti-inflammatory effects. The aim of the current study was to investigate the anti-inflammatory effects of ghrelin, in a rat model of SCI.