The effect of some antibiotics on polymorphonuclear leukocyte (PMN) functions and PMN's myeloperoxidase activity, glutathione and malondialdehyde levels of patients with type 2 diabetes mellitus in vitro


RAYAMAN P. , RAYAMAN E. , Cevikbas A., Demirtunc R., Sehirli A. O. , Gurer Ü.

CLINICAL AND EXPERIMENTAL HEALTH SCIENCES, vol.3, no.4, pp.200-207, 2013 (Journal Indexed in ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 3 Issue: 4
  • Publication Date: 2013
  • Doi Number: 10.5455/musbed.20131215110852
  • Title of Journal : CLINICAL AND EXPERIMENTAL HEALTH SCIENCES
  • Page Numbers: pp.200-207

Abstract

Objective: In this study, our objective was to compare PMN functions and myeloperoxidase (MPO) activity, glutathione (GSH) and malondialdehyde (MDA) levels and assess the relationship between PMN functions and enzyme levels in patients with type 2 diabetes mellitus (T2DM) and healthy volunteers. We also examined the immunomodulatory effects of ciprofloxacin, rifampicine and doxycycline on PMN functions, MPO activity and GSH and MDA levels.