Lymphocyte Functions in Patients with Chronic Granulomatous Disease and Carrier Individuals

ÖĞÜLÜR İ., Barış E., KIYKIM A., Başer D., Akgün G., ÖZEN A. O., ...Daha Fazla

TURKISH JOURNAL OF IMMUNOLOGY, cilt.7, sa.2, ss.93-101, 2019 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 7 Sayı: 2
  • Basım Tarihi: 2019
  • Doi Numarası: 10.25002/tji.2019.1111
  • Dergi Adı: TURKISH JOURNAL OF IMMUNOLOGY
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.93-101
  • Anahtar Kelimeler: Chronic granulomatous disease, lymphocyte, proliferation, Treg, intracellular cytokines, X-LINKED CARRIERS, REGULATORY T-CELLS, MANIFESTATIONS
  • Marmara Üniversitesi Adresli: Evet

Özet

Introduction: Chronic granulomatous disease (CGD) is classically known as phagocytic system disease. However, in recent years, the observation of the development of autoimmunity, colitis-like findings during follow-up has suggested that the acquired immune system may also be defective. The aim of this project is to investigate the percent of T and B lymphocytes, and function of T lymphocytes in patients with CGD and carriers.