Lymphocyte Functions in Patients with Chronic Granulomatous Disease and Carrier Individuals


ÖĞÜLÜR İ. , Barış E. , KIYKIM A., Başer D., Akgün G., ÖZEN A. O. , ...More

TURKISH JOURNAL OF IMMUNOLOGY, vol.7, no.2, pp.93-101, 2019 (Journal Indexed in ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 7 Issue: 2
  • Publication Date: 2019
  • Doi Number: 10.25002/tji.2019.1111
  • Title of Journal : TURKISH JOURNAL OF IMMUNOLOGY
  • Page Numbers: pp.93-101
  • Keywords: Chronic granulomatous disease, lymphocyte, proliferation, Treg, intracellular cytokines, X-LINKED CARRIERS, REGULATORY T-CELLS, MANIFESTATIONS

Abstract

Introduction: Chronic granulomatous disease (CGD) is classically known as phagocytic system disease. However, in recent years, the observation of the development of autoimmunity, colitis-like findings during follow-up has suggested that the acquired immune system may also be defective. The aim of this project is to investigate the percent of T and B lymphocytes, and function of T lymphocytes in patients with CGD and carriers.