Effect of inhaled steroids on clinical and inflammatory parameters in children with cystic fibrosis

Uyan Z. S., Unluguzel Ustun G., HAKLAR G., Cakir E., Oktem S., Ersu R., ...Daha Fazla

TURKISH JOURNAL OF MEDICAL SCIENCES, cilt.47, sa.5, ss.1432-1440, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 47 Sayı: 5
  • Basım Tarihi: 2017
  • Doi Numarası: 10.3906/sag-1509-101
  • Dergi Adı: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.1432-1440
  • Anahtar Kelimeler: Antiinflammatory treatment, children, cystic fibrosis, glucocorticoids, inhalation, RANDOMIZED CONTROLLED-TRIAL, LUNG-FUNCTION DECLINE, FLUTICASONE PROPIONATE, ANTIINFLAMMATORY THERAPIES, AIRWAY INFLAMMATION, YOUNG-CHILDREN, LONG-TERM, CORTICOSTEROIDS, SPUTUM, METHACHOLINE
  • Marmara Üniversitesi Adresli: Evet

Özet

Background/aim: The effectiveness of inhaled corticosteroids (ICSs) in cystic fibrosis (CF) is controversial. The aim of this study was to investigate the effect of an ICS on bronchial hyperreactivity (BHR), oxidative status, and clinical and inflammatory parameters in CF patients.