Belirgin kardiyovasküler hastalığı olmayan hastalarda COVID-19 mRNA aşısının elektrokar-diyografik parametreler üzerinde herhangi bir etkisi var mı?


Küp A., Çelik M., Uslu A., Külahçıoğlu Ş., Tükenmez Tigen E., Demir S., ...More

Troia Medical Journal, vol.3, no.3, pp.96-99, 2022 (Peer-Reviewed Journal)

  • Publication Type: Article / Article
  • Volume: 3 Issue: 3
  • Publication Date: 2022
  • Doi Number: 10.55665/troiamedj.1151301
  • Journal Name: Troia Medical Journal
  • Journal Indexes: Asos İndeks
  • Page Numbers: pp.96-99
  • Marmara University Affiliated: Yes

Abstract

Objective: Electrocardiographic alterations were investigated following the second dosage of COVID-19 mRNA vaccination. Methods: A total of 260 individuals after two doses of COVID-19 vaccine with Pfizer-BioNTech were included in the study. The electrocardiographic parameters recorded at baseline and approximately one week later after two doses of Pfizer-BioNTech vaccine were compared for all patients. Results: PR interval was increased and QTc maximum interval was decreased significantly after second dose COVID-19 mRNA vaccination. Baseline and post-second dose vaccination states regarding P wave dispersion and QT dispersion/Tp-e interval which have been recognized to imply inhomogeneous atrial conduction and heterogeneity in ventricular repolarization were similar between groups. Conclusion: Our findings suggest that there should be no concern related to asymptomatic involvement of the myocardium subsequent the second dose of COVID-19 mRNA vaccination.