Ga-68-Prostate-Specific Membrane Antigen PET-Positive Paget Bone Disease With Metastatic Prostatic Carcinoma


ENGÜR C. Ö. , TUROĞLU H. T. , ÖZGÜVEN S. , TANIDIR Y. , ERDİL T. Y.

CLINICAL NUCLEAR MEDICINE, vol.45, no.9, 2020 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Editorial Material
  • Volume: 45 Issue: 9
  • Publication Date: 2020
  • Doi Number: 10.1097/rlu.0000000000003198
  • Title of Journal : CLINICAL NUCLEAR MEDICINE

Abstract

Paget bone disease is a chronic benign bone disease characterized by excessive and abnormal bone remodeling. The scintigraphic and bone SPECT/CT hybrid imaging appearances of the affected bone(s) depend on the stage of the disease. We report the case of a patient newly diagnosed with prostate cancer who was found to have multiple osseous metastases, with coexisting Paget disease in the left hemipelvis diagnosed because of typical scintigraphic and SPECT/CT appearance.Ga-68-prostate-specific membrane antigen PET/CT was also performed for initial staging. Pagetoid bones showed increased prostate-specific membrane antigen uptake like skeletal metastases.