Molecular Mechanism and Targets of the Antimicrobial Activity of Metal Nanoparticles

OKTAR F. N., YETMEZ M., Ficai D., Ficai A., Dumitru F., Pica A.

CURRENT TOPICS IN MEDICINAL CHEMISTRY, cilt.15, sa.16, ss.1583-1588, 2015 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 15 Sayı: 16
  • Basım Tarihi: 2015
  • Dergi Adı: CURRENT TOPICS IN MEDICINAL CHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1583-1588
  • Anahtar Kelimeler: Antibacterial, Antiviral, Drug-multiresistant bacteria, Molecular mechanism, SILVER NANOPARTICLES, ANTIBACTERIAL ACTIVITY, ESCHERICHIA-COLI, GOLD NANOPARTICLES, MEDIATED TOXICITY, MGO NANOPARTICLES, DOPED TIO2, ZNO, COPPER, NANOMATERIALS
  • Marmara Üniversitesi Adresli: Evet

Özet

The emergence of multi-resistant bacteria to drugs is recognized as a major cause of the increasing number of deaths in hospitals. Killing these bacteria require multiple expensive drugs that can have side effects. Metal nanoparticles may provide a new strategy to combat them. Due the antimicrobial and antiviral properties, nanoparticles (NPs) have outstanding biological properties that can be handled properly for desired applications. This review presents antibacterial and antiviral activity of metal NPs, including the molecular mechanisms by which NPs annihilate multidrug-resistant bacteria.