The Novel Function of Nesfatin-1 as an Anti-inflammatory and Antiapoptotic Peptide in Subarachnoid Hemorrhage-Induced Oxidative Brain Damage in Rats

ÖZSAVCI D. , Ersahin M., ŞENER A. , BİNGÖL ÖZAKPINAR Ö. , Toklu H. Z. , AKAKIN D. , ...More

NEUROSURGERY, vol.68, no.6, pp.1699-1708, 2011 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 68 Issue: 6
  • Publication Date: 2011
  • Doi Number: 10.1227/neu.0b013e318210f258
  • Title of Journal : NEUROSURGERY
  • Page Numbers: pp.1699-1708
  • Keywords: Apoptosis, Nesfatin-1, Neutrophils, Oxidative stress, Subarachnoid hemorrhage, IMMUNOREACTIVITY, VASOSPASM, BARRIER, PERMEABILITY, INFLAMMATION, EXPRESSION, MORTALITY, NEURONS, INJURY, DYE

Abstract

BACKGROUND: There is substantial evidence to suggest that oxidative stress plays a significant role in the development of acute brain injury after subarachnoid hemorrhage (SAH).