Apocynin attenuates testicular ischemia-reperfusion injury in rats


Sener T. E. , YÜKSEL M. , Ozyilmaz-Yay N., ERCAN F. , Akbal C., ŞİMŞEK F. , ...More

JOURNAL OF PEDIATRIC SURGERY, vol.50, no.8, pp.1382-1387, 2015 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 50 Issue: 8
  • Publication Date: 2015
  • Doi Number: 10.1016/j.jpedsurg.2014.11.033
  • Title of Journal : JOURNAL OF PEDIATRIC SURGERY
  • Page Numbers: pp.1382-1387
  • Keywords: Spermatic cord torsion, Testis, Reperfusion injury, Apocynin, OXIDATIVE STRESS, NADPH OXIDASE, FREE-RADICALS, DAMAGE, GLUTATHIONE, MECHANISMS, HYPERTENSION, INFLAMMATION, SUPEROXIDE, EXPRESSION

Abstract

Objective: This study was designed to examine the possible protective effect of apocynin, a NADPH oxidase inhibitor, against torsion/detorsion (T/D) induced ischemia/reperfusion (I/R) injury in testis.